See BSim in Action
To showcase the breadth of problems that can be tackled with BSim and some of our favourite examples, this gallery contains a selection of movies generated using BSim.
Emergent Oscillations in Synthetic Microbial Consortium
Two populations of bacteria, Repressors (green) and Activators (blue), mutually interact with one another through quorum sensing molecules. The resulting feedback loop induces oscillations in the joint population.
A Consortium Feedback Controller
Controller cells (blue) receive an external input. Target cells (red), unaware of this input, receive instead a quorum moelcule from the Controllers. The Controllers sense the output of the Targets, compare it to the external input, and modulate their feedback accordingly driving the Targets toward the desired output.
Vesicle Excretion
A population of bacteria (green) excreting outer membrane vesicles (red fuzzy dots) that then spread through the environment due to Brownian forces.
Swarm Protection
Two bacterial populations, one (green) killed by toxic molecules (yellow dots) and the other (purple) not. The unaffected population generates outer membrane vesicles (purple fuzzy dots) that degrade the dangerous molecule and helps protect the other population.
Multicellular Computing with Bacterial Populations
Four populations of bacteria, communicate using diffusible chemicals and implements a multi-stage logic function. Eventually after an initial transient, a stable pattern develops encoding the final solution to the logic function.
Synchronisation of Synthetic Genetic Oscillators
A bacterial population of genetic oscillators start off with random initial condition, but become synchronisation through communication using a diffusible chemical that is produced and sensed by all the cells. In the end you see all cells oscillating in union.
